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butabarbital will lower the level or impact of fedratinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Impact of coadministering a strong CYP3A4 inducer with fedratinib hasn't been researched.butabarbital will minimize the level or outcome of glecaprevir/pibrentasvir by impacting hepatic/intestinal